According to recent statistics the rising incidence of skin cancer is one of the main problems in United States. Considering that this condition appears to be becoming an epidemic, very critical is to develop new approaches to primary and secondary prevention. As consequences we can see many studies exploring the therapeutic value of natural ingredients and researches suggest that common fruit and vegetables extracts may have an important clinical benefits in lowering risk for skin cancer.

It is well-known that fruits and vegetables contain a variety of minerals and vitamins and other bioactive substances that include lutein, flavonoids, folic acid, vitamins C and E, and fiber. The folic acid has a key role in repair and synthesis of DNA, and all dark green leafy vegetables are very rich in it. So, new findings show with no doubt that higher intakes of green leafy vegetables may help prevent Squamous cell carcinoma (SCC) tumors among patients who have prior skin cancers.

Another new finding is that pigment that gives certain fruits their dark red colors has an antioxidant activity higher than that of green tea and red wine. Researchers evaluated that pomegranate fruit extract (PFE) is capable of inhibiting conventional as well as new biomarkers of TPA-induced tumors and they may have chemopreventive action in a wide category of tumor models.